Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Physics-Informed Neural Network-Enabled Forward Prediction and Inverse Design of Ring Origami.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Spatiotemporal modulation of surface texture for information encoding and object manipulation.

Nature communications·2026

Same author

Stroke Severity and Functional Benefit of Thrombectomy in Acute M2 Middle Cerebral Artery Occlusion: A Multicenter Cohort Study.

Neurology·2026

Same author

Ischemic Lesion Net Water Uptake Outperforms ASPECTS and CBF Less Than 30% in Predicting Futile Recanalization after Mechanical Thrombectomy.

Radiology·2026

Same author

Rod Origami (RodOri) Spring Metamaterials for Tunable Vibration Control via Tailored Structural Instabilities.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Woven Endobridge device for ruptured vs. unruptured aneurysms: insights from the WorldWideWEB study.

Neuroradiology·2026

Same journal

Incoming US science academy chief vows to 'double down' on research.

Nature·2026

Same journal

Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization.

Nature·2026

Same journal

Electrodeposited self-assembled molecules for perovskite photovoltaics.

Nature·2026

Same journal

Neutrino's nursery found: the 'Shadow Blaster'.

Nature·2026

Same journal

Dementia risk in middle-aged people linked to a blood protein.

Nature·2026

Same journal

Daily briefing: What's really happening with trust in science.

Nature·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 5, 2026

Prehospital Thrombolysis: A Manual from Berlin

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Milli-spinner thrombectomy.

Yilong Chang¹, Shuai Wu¹, Qi Li¹

¹Department of Mechanical Engineering, Stanford University School of Engineering, Stanford, CA, USA.

|June 4, 2025

Summary

This summary is machine-generated.

A novel milli-spinner device effectively removes arterial and venous clots by densifying their structure, improving mechanical thrombectomy success rates. This innovative approach offers faster, more complete clot removal for conditions like stroke and pulmonary embolism.

More Related Videos

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Published on: September 25, 2016

Simulator Training for Endovascular Neurosurgery

Simulator Training for Endovascular Neurosurgery

Published on: May 6, 2020

Related Experiment Videos

Last Updated: May 5, 2026

Prehospital Thrombolysis: A Manual from Berlin

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Published on: September 25, 2016

Simulator Training for Endovascular Neurosurgery

Simulator Training for Endovascular Neurosurgery

Published on: May 6, 2020

Area of Science:

Biomedical Engineering
Cardiovascular Research
Medical Devices

Background:

Arterial and venous clots cause severe medical conditions, necessitating effective clot removal techniques.
Mechanical thrombectomy is a minimally invasive procedure for treating various vascular diseases, but current methods have limitations.
Existing thrombectomy techniques struggle with large, fibrin-rich clots and risk clot fragmentation, leading to poor patient outcomes.

Purpose of the Study:

To develop an innovative mechanical thrombectomy device that overcomes the limitations of current methods.
To modify clot microstructure for enhanced removal, improving success rates in treating vascular blockages.
To introduce the milli-spinner thrombectomy as a superior alternative for clot removal.

Main Methods:

Development of the milli-spinner thrombectomy device utilizing mechanical densification and shear forces.
In vitro testing using pulmonary and cerebral artery flow models.
In vivo experimentation in swine models to evaluate device performance.

Main Results:

The milli-spinner thrombectomy shrinks clot volume by up to 95% through mechanical densification.
Demonstrated ultrafast clot debulking and high-fidelity revascularization in both in vitro and in vivo models.
Outperformed traditional aspiration thrombectomy in clot removal efficiency and outcomes.

Conclusions:

The milli-spinner thrombectomy directly modifies clot microstructure, facilitating easier and faster removal.
This novel approach significantly improves mechanical thrombectomy success rates compared to current clot-rupturing or cutting methods.
The milli-spinner offers a promising advancement for treating ischaemic stroke, pulmonary embolism, and peripheral thrombosis.