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Thalamic 1H-MR spectroscopy in vestibular and episodic migraine
Hazal Selvi Çubuk1,2, Can Çubuk3,4, Şebnem Bıçakcı3
1Department of Radiology, Cukurova University Faculty of Medicine, Adana, Turkey.
Objectives:
The aim of the study was to evaluate the metabolite changes in thalamus that patients with vestibular and episodic migraine.
Methods:
Fifteen patients with vestibular migraine and 15 patients with episodic migraine that had been diagnosed at the Cukurova University Neurology Department were included in this prospective study. Magnetic resonance spectroscopy (MRS) was obtained in the interictal period at 3 Tesla MR 32-channel head coil. SPSS v20 was used for the statistical analysis.
Results:
Left thalamus posterior choline value (Choline 4) was found to be lower in patients with vestibular migraine (p = 0.009). The analysis of NAA/Choline values between the groups did not reveal any significant difference (p > 0.05).
Conclusion:
Metabolite changes in the thalamus in vestibular and episodic migraine patients could provide information about the pathophysiology of the disease and may help explain the different mechanisms of episodic migraine and VM occurrence.
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