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Tumor Progression02:07

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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Are We Off the Hook? An Update in Breast Localisation Trends.

Sian Chin1, Sally Burrows2,3, Donna Taylor1,2,4

  • 1Royal Perth Hospital, Perth, Western Australia, Australia.

Journal of Medical Imaging and Radiation Oncology
|June 5, 2025
PubMed
Summary

Hookwire localisation remains the most common breast lesion localisation technique, but non-wire methods are increasingly adopted. Familiarity and cost influence technique selection in Australia and New Zealand.

Keywords:
breast imagingmammarymastectomysegmentalultrasonography

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Area of Science:

  • Breast surgery
  • Surgical oncology
  • Medical device technology

Background:

  • Hookwire localisation (HWL) is the established standard for impalpable breast lesion localisation.
  • A 2016 study identified HWL as the most prevalent breast lesion localisation technique (LLT) among Australian and New Zealand surgeons.
  • Emerging non-wire techniques aim to overcome HWL limitations.

Purpose of the Study:

  • To evaluate current trends in breast lesion localisation techniques (LLTs) in Australia and New Zealand.
  • To compare contemporary LLT usage with findings from a 2016 study.
  • To identify factors influencing the choice of breast lesion localisation methods.

Main Methods:

  • An online survey was distributed to national Breast Conference attendees.
  • The survey was conducted between March 25 and April 21, 2023.
  • 100 complete responses were analyzed.

Main Results:

  • Hookwire localisation (HWL) was used by 95% of respondents, and 73% cited it as their most used LLT.
  • Non-wire techniques like Magseed (30%) and Carbon-track (26%) show increasing adoption.
  • Radioguided techniques saw a significant increase in use from 4% to 13% since 2016 (p=0.036).

Conclusions:

  • Hookwire localisation (HWL) continues to be the dominant breast lesion localisation technique.
  • There is a notable increase in the utilization of non-wire localisation techniques.
  • Factors such as surgeon familiarity and cost significantly impact the selection of breast lesion localisation methods.