Effects of 2100 MHz radio-frequency fields on brain tissues and plasma of normal rats and obese rats

The use of mobile phones, one of the popular recent sources of radio-frequency fields (RFF), is increasing. It has been shown thatRFF exposure can increase free radical levels and oxidative stress.Obesity is an important risk factor for many diseases such as cancer, cardiovascular diseases, and diabetes, and has been shown to increase oxidative stress. In this study, rats were exposed to 2100 MHz RFF(electric field 15 V/m) for 15 minutes daily and 4 hours daily for 3 weeks. It aims to investigate the effects of 2100 MHz RFF on brain tissue and plasma of normal and obese rats. The rats were divided into eight groups (n = 6):control, Sham1, Sham2, RFF1, RFF2, High Fat Diet (HFD), Sham+HFD, andHFD+RFF. The inflammatory and oxidative effects on brain tissue and plasma were analyzed using the GraphPad 9 macOS package program. WhenTOS levels in brain tissue were compared between Sham2 and RFF1 andall groups, a significant difference was found in the RFF2 group. TASlevel was significantly different in the HDF+RFF group compared to the control group, Sham and all groups. When pro-inflammatory and anti-inflammatory parameters were evaluated in brain tissue, significant differences were found in different exposure groups. Inplasma, TOS levels were significantly different in the RFF2 groupcompared to Sham2 and RFF1, but TAS levels were not different.According to the data obtained, obesity may be protective against the oxidative and inflammatory effects of RFF.