Pharmacogenomic testing and implications for psychiatric medication prescribing
1Rose Mary Xavier is assistant professor and director of the Biobehavioral Laboratory at the University of North Carolina at Chapel Hill School of Nursing in Chapel Hill, N.C.
Abstract:
A pharmacogenomics-informed prescribing strategy examines genetic variations in individual patients for more personalized selection and dosing of psychiatric medications for which a clinical evidence base and/or clinical guidelines exist. Clinicians who prescribe psychiatric medications should be aware of the pharmacogenomic evidence base and existing guidelines relevant to medication selection, dosing, and interactions to ensure safe and effective treatment. Although pharmacogenomic testing does not replace current prescribing strategies, when used alongside them, it acts as a valuable clinical decision support tool that can improve the selection and dosing of specific psychiatric medications.
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