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Related Concept Videos

Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-IV: Diagnostic and Management01:30

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
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Asthma-IV: Nursing Management01:30

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Asthma: Biomedical and Psychobiological Perspectives.

Thomas Ritz1, Melissa A Rosenkranz, Juan C Celedón

  • 1Department of Psychology, Southern Methodist University, Dallas, Texas, (Ritz); Center for Healthy Minds, and Department of Psychiatry, University of Wisconsin-Madison, Madison, Wisconsin, (Rosenkranz); Department of Pediatrics, Division of Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, (Celedón); Department of Physiological Sciences, University of Florida, Gainesville, Florida, (Davenport); Faculty of Medicine, Clinical and Experimental Sciences and Human Development and Health, University of Southampton, and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK (Djukanovic); Ferkauf Graduate School of Psychology, Yeshiva University, and Department of Pediatrics, Division of Academic General Pediatrics, Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, New York, New York, (Feldman); Department of Medicine, Division of Pulmonary Medicine, Alberta Respiratory Centre, University of Alberta, Edmonton, Canada (Forsythe); University of Wisconsin-Madison School of Medicine and Public Health, Pulmonary and Critical Care Division, Madison, Wisconsin, (Jajour); Department of Cellular and Molecular Medicine, Asthma and Airway Disease Research Center, BIO5 Institute, and Arizona Center for the Biology of Complex Diseases, University of Arizona, Tucson, Arizona, (Vercelli); Research Group Health Psychology, KU Leuven, Leuven, Belgium (von Leupoldt); Department of Environmental Medicine, Department of Public Health, and Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, New York, (Wright).

Biopsychosocial Science and Medicine
|June 5, 2025
PubMed
Summary

Asthma research integrates biomedical and psychobiological insights, highlighting the need for further study on gene-microbiome-psychosocial interactions and brain-body connections for holistic treatment.

Keywords:
asthmabiopsychosocial treatmentdiversityetiologyinteroceptionpathophysiologypsychobiology

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Area of Science:

  • Integrative medicine
  • Psychoneuroimmunology
  • Asthma research

Background:

  • Decades of biomedical and psychobiological research have advanced asthma understanding.
  • Psychosocial factors significantly influence asthma development, pathophysiology, and management.
  • Gaps remain in understanding gene-microbiome-psychosocial interactions in asthma.

Purpose of the Study:

  • To report on synergistic perspectives from biomedical and psychobiological research on asthma.
  • To identify areas for future research in asthma mechanisms and treatment.
  • To promote an integrative, biopsychosocial approach to asthma care.

Main Methods:

  • Discussion at the American Psychosomatic Society's first Annual Disease-A-Year Symposium.
  • Review of progress in identifying asthma's mechanical, cellular, and molecular mechanisms.
  • Exploration of psychosocial influences on asthma.

Main Results:

  • Progress in understanding asthma mechanisms and psychosocial influences.
  • Emerging focus on central nervous system effects and brain-body interaction in asthma.
  • Recognition of societal factors impacting asthma disparities and resilience.

Conclusions:

  • Further research is needed on gene-microbiome-psychosocial interactions and central nervous system effects.
  • An integrative, biopsychosocial model is crucial for holistic asthma treatment.
  • Interdisciplinary collaboration is essential for advancing asthma care and improving patient outcomes.