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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Accessory Structures of the Skin: Sebaceous Glands01:21

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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Papillary Dermis01:11

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Updated: Sep 19, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

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Guttate Psoriasis: Another Kid With an Itchy Rash.

Teresa Dodge1

  • 1Author Affiliations: US Acute Care Solutions, Guthrie Cortland Medical Center, Cortland, NY.

Advanced Emergency Nursing Journal
|June 5, 2025
PubMed
Summary
This summary is machine-generated.

Guttate psoriasis (GP) is an immune-mediated skin condition affecting young adults and children. This distinct psoriasis variant typically presents as an acute rash following a streptococcal infection.

Keywords:
dermatologyguttate psoriasisrashtear-shaped plaques

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Area of Science:

  • Dermatology
  • Immunology

Background:

  • Guttate psoriasis (GP) is a specific variant of psoriasis, a common immune-mediated skin disorder.
  • Psoriasis affects 2-4% of the global population, with GP accounting for approximately 30% of cases.
  • GP predominantly impacts children and young adults.

Purpose of the Study:

  • To define guttate psoriasis as a distinct dermatological condition.
  • To highlight the characteristic triggers and patient demographics associated with GP.

Main Methods:

  • Review of epidemiological data on psoriasis prevalence.
  • Clinical case analysis of guttate psoriasis presentations.
  • Identification of immune-mediated pathways in GP pathogenesis.

Main Results:

  • Guttate psoriasis is characterized by an acute rash.
  • Streptococcal infection is a classic preceding factor for GP onset.
  • GP primarily affects pediatric and young adult populations.

Conclusions:

  • Guttate psoriasis is a unique immune-mediated dermatological disorder.
  • Understanding GP's distinct features, particularly its association with streptococcal infections, is crucial for diagnosis and management.