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Updated: Sep 19, 2025
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
Sentinel lymph node biopsy in early oral cavity tumors: Evaluation of the oncologic efficacy compared to elective
Marco Roberto Seferin1, Fábio Roberto Pinto2, Chin Shien Lin3
1Universidade de São Paulo (USP), Faculdade de Medicina (FM), Programa de Pós-Graduação, São Paulo, SP, Brazil.
Objective:
To describe the oncological results of a prospective study in the use of sentinel lymph node biopsy as part of the surgical treatment of squamous cell carcinoma T1/T2N0 of the oral cavity in comparison to the results of patients submitted to levels I, II and III SND.
Methods:
It was a prospective study in which seventy patients were divided into two groups, 35 being submitted to SND and the other 35 to SLB.
Results:
In the SND group, locoregional recurrence occurred in 17.1%, with a 2.9% development of distant metastasis and 8.8% evolved with a second primary tumor. In the SLB, locoregional recurrence was observed in 7 patients (20.0%), 5.7% developed distant metastasis, and 5.7% had a second primary tumor. There was no significant difference between the two groups for both overall (p = 0.521) and disease-free survival (p = 0.753).
Conclusion:
A SLB is reliable for the management of clinically negative neck in patients with oral T1/T2N0 squamous cell carcinoma.
Level Of Evidence:
Level III.
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