Related Experiment Video
Updated: Sep 19, 2025

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Impact of menopause education interventions on knowledge, symptoms and quality of life: protocol for a systematic
Abigail Marco1, Elizabeth Lorenzo2, Jennifer DeBerg3
1College of Nursing, University of Iowa, Iowa City, Iowa, USA.
Introduction:
The menopause transition is a critical period of life for women associated with a variety of symptoms that may impact health status and quality of life. Menopause education can improve menopause knowledge and self-efficacy, leading to the adaptation of self-management strategies that may reduce menopause symptom burden and enhance quality of life. The purpose of this review is to systematically evaluate the research on the effect of menopause education interventions among midlife women (age 35-55 years) on menopause knowledge, self-efficacy, symptoms and quality of life.
Methods And Analysis:
This protocol is guided by the 2015 Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols. We will comprehensively search for articles published from all publication years through December 2024 in PubMed, Embase, CINAHL, PsycINFO, ProQuest Dissertation and Theses, and Scopus. The search strategy will include the following key terms and Medical Subject Headings terms: 'menopause', 'menopausal', 'menopause transition', 'climacteric', 'health promotion', 'health education' and 'patient education'. Eligible studies will be experimental or quasi-experimental and include midlife women (age 35-55 years) who have received a menopause education intervention. Studies must report on the impact of menopause education interventions on menopause knowledge, self-efficacy, symptoms or quality of life. Only peer-reviewed articles and dissertations in English and Spanish will be included. Behavioural interventions (diet, physical activity, yoga) and medical interventions will be excluded. Two reviewers will independently perform data extraction and assess study quality/risk of bias with the Cochrane Risk of Bias tool for randomised experimental studies (RoB2) and the Risk of Bias in Non-Randomized Studies of Interventions tool (ROBINS-I). A narrative approach will be used to synthesise findings.
Ethics And Dissemination:
Ethical approval is not required for this systematic review of published literature. Findings will be disseminated via peer-reviewed journal publications, presentations at professional scientific meetings and social media.
Prospero Registration Number:
CRD42024599106.
More Related Videos
Related Concept Videos
Menopause
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
Hormonal Regulation
Disorders of the Female Reproductive System
Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...

