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Updated: Jun 13, 2025

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
[Pediatric cataract-part 2 : Surgical treatment]
Thomas Kohnen1, Yaroslava Wenner2, Maria Fronius2
1Klinik für Augenheilkunde, Klinikum der Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland. kohnen@em.uni-frankfurt.de.
Insights
Pediatric cataract surgery requires specialized knowledge due to unique risks and outcomes in children. Early infant surgery for congenital cataracts significantly increases the risk of aphakic glaucoma, a major long-term complication.
Area of Science:
- Ophthalmology
- Pediatric Surgery
Background:
- Pediatric cataract surgery differs significantly from adult procedures.
- Understanding age-specific risks, ocular/systemic conditions, and amblyogenic potential is crucial for pediatric cataract treatment planning.
- Increased surgical risks and individual amblyogenic risk influence treatment decisions.
Purpose of the Study:
- To provide an overview of key considerations in pediatric cataract treatment.
- To highlight the unique challenges and long-term outcomes associated with pediatric cataract surgery.
Main Methods:
- Review of current literature and established knowledge on pediatric cataract surgery.
- Analysis of risk factors influencing surgical versus non-surgical treatment decisions.
- Discussion of common complications and their associated risk factors.
Main Results:
- Aphakic glaucoma is the most frequent long-term complication following congenital cataract surgery in children.
- Surgery performed during early infancy is the primary risk factor for developing aphakic glaucoma.
- Additional risk factors for aphakic glaucoma include microphthalmos, fetal nuclear cataract, and persistent fetal vasculature.
Conclusions:
- Pediatric cataract treatment necessitates a comprehensive approach, considering surgical techniques, patient age, and associated comorbidities.
- Proactive management and awareness of risk factors are essential to mitigate complications like aphakic glaucoma in pediatric patients.
Abstract:
Pediatric cataract surgery is very different from adult cataract surgery. A profound understanding of surgical technique, age at time of surgery, combined ocular and systemic diseases to be associated with long-term functional or morphological outcomes is important for planning and performing treatment of cataracts in children. Increased intra- and postoperative risk and individual amblyogenic risk mainly affect surgical versus nonsurgical treatment decisions. The most common long-term complication in children following congenital cataract surgery is aphakic glaucoma. It is well established that the single greatest risk factor for aphakic glaucoma is surgery during early infancy. Other risk factors include microphthalmos, fetal nuclear cataract, and persistent fetal vasculature. The following article provides an overview on important aspects of pediatric cataract treatment.
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