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Updated: Jun 13, 2025
07:13
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
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Medication Adherence Status and Influencing Factors in Adolescent Kidney Transplant Recipients
Yanhua Li1, Yutong Chen1, Shijun Pu1
1Department of Organ Transplantation, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Pediatric Transplantation
|June 6, 2025
Summary
Most adolescent kidney transplant recipients show poor medication adherence, linked to post-transplant complications and lower perceived medication necessity. Improving adherence requires monitoring complications and enhancing patient understanding of immunosuppressive drug importance.
Area of Science:
- Nephrology
- Transplantation
- Adolescent Medicine
Background:
- Investigating medication adherence in adolescent kidney transplant recipients is crucial for long-term graft survival.
- Immunosuppressive drug regimens are vital post-transplant, necessitating high adherence rates.
Purpose of the Study:
- To assess medication adherence levels in adolescent kidney transplant recipients.
- To identify factors influencing medication adherence in this population.
Main Methods:
- Convenience sampling of 115 adolescent kidney transplant recipients from four Chinese tertiary hospitals.
- Utilized questionnaires assessing general information, adherence, medication beliefs, and overall happiness.
- Data collected between February and October 2023.
Main Results:
- 60.08% of recipients exhibited poor medication adherence.
- Graft failure occurred in 6.5% of patients with poor adherence; none in those with excellent adherence.
- Post-transplant rejection, infections, perceived medication necessity, and overall happiness significantly impacted adherence.
Conclusions:
- High rates of poor adherence necessitate focused monitoring of post-transplant complications.
- Enhancing recipients' understanding of medication necessity and psychological well-being is key.
- Early warning systems during follow-up can facilitate timely interventions to improve adherence.
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