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Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case report
Quang Trung Nguyen1, Van Diep Pham1, Quoc Dat Tran1
1Radiology Center, Hanoi Medical University Hospital, Hanoi, Vietnam.
Radiology Case Reports
|June 6, 2025
Summary
Small field-of-view diffusion-weighted imaging (sFOV DWI) successfully detected a small insulinoma missed by conventional scans. This advanced MRI technique improves localization for effective surgical treatment of pancreatic neuroendocrine tumors.
Area of Science:
- Endocrinology
- Oncology
- Radiology
Background:
- Insulinoma, a rare pancreatic neuroendocrine tumor, causes recurrent hypoglycemia and requires precise preoperative localization for successful surgical resection.
- Conventional imaging modalities like ultrasound, CT, and standard MRI can fail to detect small insulinomas, complicating diagnosis and surgical planning.
Observation:
- A 57-year-old female presented with recurrent hypoglycemia, but her insulinoma was not visible on ultrasound, CT, or standard MRI.
- Small field-of-view diffusion-weighted imaging (sFOV DWI) identified a 13x10 mm lesion in the pancreatic body and tail.
Findings:
- The lesion identified by sFOV DWI exhibited imaging characteristics consistent with a pancreatic neuroendocrine tumor.
- Histopathological examination confirmed the diagnosis of insulinoma following surgical resection.
Implications:
- sFOV DWI is a valuable tool for detecting small pancreatic lesions, especially when conventional imaging is insufficient.
- This technique can significantly enhance diagnostic accuracy and guide surgical planning for challenging insulinoma cases, potentially improving patient outcomes.
