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Drug-induced stuttering: A case study.

Thales De Nardo¹, Elizabeth A Minton²

¹Department of Communication Sciences & Disorders, Western Carolina University, United States.

Journal of Fluency Disorders

|June 6, 2025

Summary

This summary is machine-generated.

This case study highlights a rare instance of persistent acquired stuttering following Gabapentin and Lexapro use. Therapy focusing on cognitive and affective factors, not just fluency, improved the patient's quality of life.

Keywords:

Acquired stuttering Case study Drug-induced stuttering Gabapentin Speech therapy

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Area of Science:

Neuroscience
Speech-Language Pathology

Background:

Acquired stuttering can be a side effect of certain medications, including Gabapentin.
Previous cases of drug-induced stuttering typically resolve after medication discontinuation.

Purpose of the Study:

To report a case of persistent acquired stuttering after Gabapentin and Lexapro use.
To evaluate the effectiveness of speech therapy targeting factors beyond fluency in acquired stuttering.

Main Methods:

A case study of a 26-year-old female with new-onset severe stuttering.
Neurological and motor speech examinations were conducted.
Speech therapy focused on secondary behaviors, cognitive, and affective aspects of stuttering.

Main Results:

The patient developed severe stuttering four days after starting Gabapentin and Lexapro.
Stuttering persisted for years despite drug discontinuation.
Standard fluency shaping strategies were ineffective.
Therapy improved cognitive, affective, quality of life, and stuttering severity measures.

Conclusions:

Gabapentin and Lexapro can cause persistent acquired stuttering.
Comprehensive speech therapy addressing cognitive and affective components is effective for acquired stuttering.
This case underscores the importance of considering non-fluency factors in treatment.