Easy Navigator: A Novel 3D Slicer-Based Neuronavigation System for Precise Brain Tumor Localization and Resection

This study evaluates the accuracy, efficiency, and clinical outcomes of a novel neuronavigation method that integrates open-source 3D Slicer software with a gyroscope-equipped pen mouse for precise resection of deep-seated brain lesions.

A retrospective analysis was conducted on 30 patients at Dr. Saad Al-Witry Neuroscience Hospital from 2020 onwards. Preoperatively, magnetic resonance imaging scans were processed into three-dimensional brain models using 3D Slicer software. Real-time intraoperative alignment was achieved by registering the virtual model with the patient's actual position with the help of a pen mouse with gyroscope guidance. System accuracy was verified with phantom models, comparative analysis with traditional neuronavigation, and direct clinical applications.

The average surgical duration was 140.07 minutes, with a consistent navigation setup time of 10 minutes. Measurement discrepancies between the Enhanced Accuracy System for Yaw-Based Navigation Navigator and actual intraoperative distances ranged from -2 mm to +2 mm, indicating high accuracy. Complete tumor resection was achieved in 73.3% of cases, with postoperative functional outcomes favorable (73.3% with modified Rankin scale score of 1; 26.7% scoring 2).

Enhanced Accuracy System for Yaw-based Navigation Navigator is used as a reliable, effective, and cost-effective neuronavigation tool. Its simplicity of use, easy installation, and precision indicate broad applicability, especially for high-precision localizations and for environments with limited resources.