Related Experiment Video

Updated: Sep 19, 2025

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
08:53

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 17, 2011

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New twist on BRCA1-mediated DNA recombination repair and tumor suppression

Dali Zong1, Raphael Pavani1, André Nussenzweig1

  • 1Laboratory of Genome Integrity, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Trends in Cell Biology
|June 6, 2025
PubMed

Keywords:
BRCA1RAD51 assemblyend resectionhomologous recombinationreplication-coupled double-strand breaktumor suppression

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