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Epigenetic regulation in early embryo development: from zygotic genome activation to the first lineage specification

Ruimin Xu1, Yanhe Li2, You Wu3

  • 1Clinical and Translation Research Center of Shanghai First Maternity and Infant Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200120, China; Frontier Science Center for Stem Cell Research, Tongji University, Shanghai, 200092, China.

Trends in Genetics : TIG
|June 6, 2025
PubMed

Keywords:
assisted reproductive technologiesearly embryoepigenetic modificationssomatic cell nuclear transferthe first lineage specificationszygotic genome activation

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