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A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
Published on: November 24, 2016
Entirely Self-Contained Electrochromic Epidermal Patch for Visualized and Multiplexed In Situ Sweat Analysis
Mengzhu Cao1, Wei Deng1, Chong-Bo Ma1
1Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education, State Key Laboratory of Integrated Optoelectronics, Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Analysis and Testing Center, Department of Chemistry, Northeast Normal University, Changchun, Jilin Province 130024, China.
This study introduces a self-contained wearable sweat sensor patch (ESEEP) that visualizes multiple biomarker levels directly on the device. This innovation enhances convenience for real-time physiological monitoring during activities like running.
Area of Science:
- Biomedical Engineering
- Wearable Technology
- Analytical Chemistry
Background:
- Wearable sweat sensors offer noninvasive physiological monitoring but often require external devices for data display.
- Limited practicality arises from the dependence on smartphones or tablets for real-time results, especially during physical activities.
Purpose of the Study:
- To develop a fully self-contained electrochromic epidermal patch (ESEEP) for visualized, simultaneous, and calibrated analysis of sweat biomarkers.
- To overcome the limitations of external display dependency in current wearable sweat sensors.
Main Methods:
- The ESEEP integrates sweat transport, sensing, control, and an electrochromic display module for integrated functionality.
- Simultaneous and multiplexed analysis of sweat metabolites and electrolytes is performed.
- The system enables real-time data visualization directly on the wearable patch.
Main Results:
- ESEEP successfully enabled simultaneous, real-time tracking of sweat glucose and sodium (Na+) in volunteers.
- The visualized results facilitated risk assessment for hypoglycemia and dehydration during exercise.
- The device demonstrated high practicality and convenience for self-monitoring.
Conclusions:
- The ESEEP represents a significant advancement in wearable technology for physiological monitoring.
- Its self-contained and self-visualized nature offers enhanced practicality and convenience for diverse diagnostic applications.
- This technology enables tailored physiological monitoring with improved user experience.

