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Synthesis of some new amidine derivatives as potent hypoglycemic agents
Pharmacological Research Communications
|August 1, 1985
Abstract:
A series of S-arylformamidino-N-(alkyl/arylisothiourea) Cyclicamino dihydrochlorides were synthesised and screened for their hypoglycemic activity in normal as well as alloxanized diabetic rats. Some of the compounds (Id, Ie, Ih-1) showed more than 30% lowering of blood sugar level of Albino rats.