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Updated: Sep 19, 2025

Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector
Published on: October 31, 2012
Generation of two human induced pluripotent stem cell lines from peripheral blood mononuclear cells featuring normal
Sanne Sandelin1, Nikolaos Giannareas1, Mikko R J Seppänen2
1Institute of Biomedicine and FICAN West Cancer Centre Laboratory, University of Turku and Turku University Hospital, FI-20520 Turku, Finland.
Abstract:
Here, we report the establishment of a human induced pluripotent stem cell (hiPSC) line TUR-STAB1-B1 derived from peripheral blood mononuclear cells of a patient carrying heterozygous mutations 52,509,890 C>A 790L>I and 52,520,515 G>A 1872R>H on STAB1 gene in addition to a normal control cell line TUR-B1. The pluripotency, identity, quality, safety, and sequence of the mutation sites of the cell lines were confirmed. The generated patient-specific cell line will facilitate detailed studies of the STAB1 in various differentiated cell types.
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