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First Metatarsophalangeal Joint Treatment Options: Allogeneic Cartilage Replacement Versus Fusion
Amber Shane1, Christopher Reeves2, Raluca Wojciechowski3
1Department of Podiatric Surgery, Advent Health System, Upperline Health, 250 N Aalafaya Trail Suite 1115, Orlando, FL 32828, USA.
Clinics in Podiatric Medicine and Surgery
|June 7, 2025
Summary
Hallux rigidus treatment options are evolving. This study compares allogeneic cartilage replacement to arthrodesis, offering alternatives for patients with first metatarsophalangeal joint arthritis.
Area of Science:
- Orthopedic surgery
- Regenerative medicine
- Foot and ankle pathology
Background:
- First metatarsophalangeal joint arthritis (hallux rigidus) is common.
- Arthrodesis is the traditional surgical standard when nonoperative treatments fail.
- Some patients prefer to avoid arthrodesis due to its irreversible nature.
Purpose of the Study:
- To analyze the efficacy of allogeneic cartilage replacement.
- To compare allogeneic cartilage replacement with arthrodesis for hallux rigidus.
- To evaluate treatment outcomes for patients seeking alternatives to fusion.
Main Methods:
- Literature review and comparative analysis.
- Examination of outcomes data for both surgical procedures.
- Assessment of patient-reported outcomes and satisfaction.
Main Results:
- Arthrodesis provides reliable pain relief and functional improvement.
- Allogeneic cartilage replacement offers a joint-preserving alternative.
- Patient preference and specific joint characteristics influence treatment choice.
Conclusions:
- Allogeneic cartilage replacement is a viable alternative to arthrodesis for select hallux rigidus patients.
- Further research is needed to establish long-term outcomes for cartilage replacement.
- Treatment decisions should be individualized based on patient factors and surgical goals.

