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Updated: May 7, 2026
Technique of Porcine Liver Procurement and Orthotopic Transplantation using an Active Porto-Caval Shunt
Published on: May 7, 2015
Recompensation after transjugular intrahepatic portosystemic shunt reduces mortality risk: A long-term follow-up
Yaowei Bai1, Jiacheng Liu1, Yu Lei1
1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Objective:
This study aims to analyze the occurrence of recompensation after transjugular intrahepatic portosystemic shunt (TIPS) for patients with cirrhosis and portal hypertension and its impact on mortality risk.
Methods:
The clinical data of 621 cirrhotic patients who underwent TIPS creation were retrospectively analyzed. Patients were categorized into a recompensation group (n = 126) and a non-recompensation group (n = 495). Binary logistic regression was used to identify independent predictors of recompensation. Kaplan-Meier (KM) survival curves were employed to assess the differences in survival between the two groups, and the Cox proportional hazards model was utilized to analyze the risk factors for mortality.
Results:
At 12 months after TIPS placement, 20.3 % of patients achieved recompensation. The recompensation group demonstrated significant improvements in both Child-Pugh and MELD scores (P < 0.05). Sarcopenia and platelet count (PLT) were identified as independent predictors of recompensation. The cumulative survival rate in the recompensation group was significantly higher than that of the non-recompensation group (HR = 2.275, 95 % CI = 1.606-3.223, Log-rank P < 0.001). Age, sarcopenia, and the occurrence of recompensation were identified as independent factors that influenced mortality risk.
Conclusion:
TIPS was associated with recompensation in certain patients, and the occurrence of recompensation is significantly associated with improved long-term survival.
