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Radiological insights into pachymeningitis imaging diagnosis: A state-of-the-art review
A Aranaz Murillo1, P Briceño Torralba1, I Marquina Ibáñez2
1Department of Radiology, Miguel Servet University Hospital, Spain.
Clinical Neurology and Neurosurgery
|June 8, 2025
Summary
Hypertrophic pachymeningitis, a dural thickening condition, requires multidisciplinary care. Early diagnosis via MRI and tailored treatment, often with corticosteroids, improves outcomes for this challenging neurological disorder.
Area of Science:
- Neurology
- Pathology
Background:
- Hypertrophic pachymeningitis involves inflammation and thickening of the dura mater.
- It presents diagnostic and management challenges due to varied clinical manifestations.
Purpose of the Study:
- To provide a comprehensive review of hypertrophic pachymeningitis.
- To emphasize a multidisciplinary approach for diagnosis and management.
Main Methods:
- Review of clinical manifestations based on lesion location (cranial vs. spinal).
- Highlighting Magnetic Resonance Imaging (MRI) as the gold standard for diagnosis.
- Discussing the differentiation between idiopathic and secondary causes.
Main Results:
- Cranial symptoms include headaches and cranial nerve issues; spinal symptoms involve back pain, radicular pain, and spinal cord compression.
- MRI provides crucial insights into dural thickening severity and complications.
- Secondary causes encompass infections, immune-mediated diseases, and neoplasms.
Conclusions:
- A multidisciplinary approach combining clinical expertise and advanced diagnostics is essential.
- Management focuses on inflammation control, primarily with corticosteroids, and potentially surgery.
- This integrated strategy aims to improve therapeutic outcomes and patient care for hypertrophic pachymeningitis.
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