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Updated: Sep 19, 2025

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Risk Factors for Postoperative Complications of Ileostomy Reversal
Si-Qi Li1, Quan Lv1, Zheng Xiang1,2
1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Complications after initial surgery increase risks for ileostomy reversal. Obesity, longer operative times, and higher American Society of Anesthesiologists (ASA) scores are key risk factors for wound infections.
Area of Science:
- Surgical outcomes
- Gastrointestinal surgery
- Meta-analysis
Background:
- Ileostomy reversal is a common surgical procedure.
- Postoperative complications can significantly impact patient recovery and outcomes.
Purpose of the Study:
- To identify risk factors for postoperative complications after ileostomy reversal.
- To compare the effectiveness of different wound closure techniques in preventing infections.
Main Methods:
- Systematic literature search of PubMed, Embase, and Cochrane Library databases.
- Meta-analysis of 19 studies involving 11,108 patients.
- Pooled analysis of odds ratios (ORs) and 95% confidence intervals (CIs) using Stata 16.
Main Results:
- Any complication after the primary procedure was associated with increased risk of ileostomy reversal complications (OR = 2.51).
- Obesity (OR = 1.45), linear wound closure (OR = 6.63), higher American Society of Anesthesiologists (ASA) scores (OR = 1.70), and longer operative time (OR = 1.30) were significant risk factors for wound infection.
- Purse-string skin closure demonstrated potential advantages in reducing incision infections compared to linear closure.
Conclusions:
- Patients with prior surgical complications require careful consideration during ileostomy reversal.
- Obesity, prolonged operative duration, and elevated ASA scores are critical risk factors for developing wound infections post-reversal.
- Purse-string skin closure may be a preferable technique for minimizing surgical site infections following ileostomy reversal.
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