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Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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Related Experiment Video

Updated: Jun 12, 2025

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

Published on: September 18, 2013

Isolated Lung Metastasis Prostate Cancer.

Emmanuel Mduma¹, Hellen Makwani¹, Said Msuya¹

¹Department of Clinical Oncology, Rabininsia Memorial Hospital, Dar es Salaam, Tanzania.

Annals of Medicine and Surgery (2012)

|June 9, 2025

Summary

Isolated lung metastasis from prostate cancer is rare, occurring in less than 4.6% of cases. This case highlights the importance of considering lung metastasis, even when isolated, in prostate cancer patients.

Area of Science:

Oncology
Urology

Background:

Prostate cancer is a leading malignancy in men globally.
Bone is the most common site for prostate cancer metastasis, with lung metastasis being rare (9.1%).

Keywords:

lung metastasis palliative care pathology prostate cancer

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Last Updated: Jun 12, 2025

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Isolated lung metastasis is exceptionally uncommon, affecting less than 4.6% of metastatic prostate cancer cases.