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Updated: Jun 12, 2025

Experimental Methods to Study Human Postural Control
Published on: September 11, 2019
Rejoinder: Nonparametric identification is not enough, but randomized controlled trials are.
P M Aronow1,2,3,4, James M Robins5,6, Theo Saarinen7
1Department of Statistics and Data Science Yale University.
Estimating treatment effects is straightforward with known propensity scores in randomized controlled trials (RCTs). However, observational studies without known propensity scores lack consistent estimators and reliable confidence intervals without untestable assumptions.
Area of Science:
- Statistics
- Econometrics
- Causal Inference
Background:
- Randomized controlled trials (RCTs) and observational studies are key empirical methods.
- Estimating average treatment effects requires assumptions like ignorability and positivity.
- Propensity scores play a crucial role in causal inference.
Purpose of the Study:
- To clarify the properties of estimators for bounded potential outcomes under ignorability and positivity.
- To differentiate estimation challenges between randomized experiments and observational studies.
- To highlight the necessity of untestable assumptions in observational causal inference.
Main Methods:
- Theoretical analysis of uniformly root-n consistent and asymptotically normal estimators.
- Examination of finite-sample valid confidence intervals and their width shrinkage rates.
- Investigation of conditions for uniform consistency and honest large-sample confidence intervals.
Main Results:
- In RCTs with known propensity scores, simple estimators are uniformly root-n consistent with valid confidence intervals.
- In observational studies with unknown propensity scores, uniform consistency and honest confidence intervals are unattainable without additional assumptions.
- Untestable assumptions on propensity score or conditional outcome functions are required for observational studies.
Conclusions:
- The presence or absence of a known propensity score fundamentally alters the statistical guarantees of causal effect estimation.
- Randomized experiments offer stronger theoretical properties for estimating average treatment effects.
- Practitioners must be aware of the limitations and required assumptions when using observational data for causal inference.
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