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Updated: Jun 12, 2025
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Published on: May 10, 2024
A Case of Type 2 Autoimmune Pancreatitis Suggesting Two Potential Disease Activity Markers
Kazuki Natsui1,2, Seiichi Yoshikawa1, Ayano Kagata1
1Department of Gastroenterology, Nagaoka Red Cross Hospital, Nagaoka, Niigata, Japan.
None:
Autoimmune pancreatitis (AIP) is divided into 2 main subtypes: type 1 AIP (AIP-1) and type 2 AIP (AIP-2). This report describes a young woman diagnosed with AIP-2 using endoscopic ultrasound-guided tissue acquisition. AIP-2 has been reported less frequently than AIP-1 as serologic abnormalities and other organ involvement except for inflammatory bowel disease are absent. Additional laboratory analyses suggest that serum interleukin-8 and leucine-rich alpha-2 glycoprotein are more efficient disease activity biomarkers than conventional C-reactive proteins. We hope that this case report will contribute to the discovery of diagnostic biomarkers for AIP-2.
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