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Updated: Jun 12, 2025

Facet-to-facet Linking of Shape-anisotropic Colloidal Cadmium Chalcogenide Nanostructures
Published on: August 10, 2017
Di-chlorido-{(E)-N,N-dimethyl-2-[phen-yl(pyridin-2-yl)methyl-idene]hydrazine-1-carbo-thio-amide}cadmium(II)
Christian S Parry1, Bernard Kwabi-Addo2, Timothy R Ramadhar3
1Department of Microbiology College of Medicine Howard University, Washington, DC 20059 USA.
Abstract:
The structure of the title compound, [CdCl2(C15H16N4S)], at 100 K has monoclinic (P21/c) symmetry. The compound has a layer structure and is a 1:1 complex of the organic ligand and cadmium chloride. The ligand, 3,3-dimethyl-1-[(E)-[phen-yl(pyridine-2-yl)methyl-idene]amino]-thio-urea (L, Bp44mT), is of inter-est with respect to anti-cancer activity, anti-viral properties and potential use in conditions of iron overload, from hemochromatosis or from multiple transfusions in hematological disorders such as sickle cell disease or beta thalassemia. This study is aimed at uncovering the basis of selectivity of the ligand as a chelator and for lead optimization. We also examine the ligand's potential use in treating heavy metal poisoning from cadmium, arsenic, lead or mercury, and for environmental remediation. The crystal structure exhibits no inter-molecular or intra-molecular hydrogen bonding with the supra-molecular features being driven by hydro-phobic, π-π and long-range dispersion forces.
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