Related Experiment Video
Updated: Jun 12, 2025

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
Published on: April 19, 2019
tert-Butyl [(4-fluoro-3-isopropoxyisoxazol-5-yl)meth-yl](phenyl-sulfon-yl)carbamate
Mohd Abdul Fatah Abdul Manan1, David B Cordes2
1Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia.
Abstract:
The title compound, C18H23FN2O6S, a new derivative of a fluoro-isoxazole containing sulfonamide functionality has been structurally characterized. The C-S-N-Cipr and C-S-N-Ccarb (ipr = 3-isopropoxyisoxazole, carb = carbamate) torsion angles are 111.1 (3)° and -70.0 (4)°, respectively. The sulfonamide functional group of this structure features S=O bond lengths of 1.403 (3) and 1.433 (3) Å, an S-N bond length of 1.672 (4) Å, and an S-C bond length of 1.753 (4) Å. The crystal packing features non-classical C-H⋯O hydrogen-bond inter-actions, with the carbonyl atom acting as a bifurcated acceptor, resulting in an R 1 2(8) ring.
More Related Videos
08:51Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core
Published on: October 24, 2017
08:56Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Related Concept Videos
Carbocations
Preparation and Reactions of Sulfides
Nucleophilic Aromatic Substitution: Elimination–Addition
Carboxylic Acids to Methylesters: Alkylation using Diazomethane
Radicals: Electronic Structure and Geometry
Accordingly, the structure of a trivalent radical lies between the geometries of carbocations and carbanions. An sp2-hybridized carbocation is trigonal planar, while an sp3-hybridized carbanion is trigonal pyramidal. Here, the difference in geometry is...
Multiple Halogenation of Methyl Ketones: Haloform Reaction