The introduction of a new mobile lifestyle tool in the battle against hypothalamic obesity; the "HAPPYthalamus" application

Area of Science:

• Pediatric Endocrinology
• Digital Health Interventions
• Behavioral Science

Background:

• Hypothalamic dysfunction in children can lead to significant weight gain, characterized by hyperphagia and reduced energy expenditure.
• The HAPPYthalamus mobile application was developed to assist these children by encouraging physical activity, providing distractions from overeating, and reinforcing healthy habits.

Purpose of the Study:

• To evaluate the usability and patient satisfaction of the HAPPYthalamus mobile app in children with hypothalamic dysfunction.
• To assess the app's potential as a supportive tool for managing weight and promoting healthier lifestyles.

Main Methods:

• A non-randomized, explorative intervention study involving children aged 8-18 with hypothalamic dysfunction and suprasellar brain tumors.
• A mixed-methods design was employed, utilizing questionnaires and semi-structured interviews to assess app usage and satisfaction over a six-month period.

Main Results:

• 15 out of 22 patients successfully learned to use the app, and 9 reported positive effects on managing hyperphagia through app-based distractions.
• The app's design required adaptation for different age groups, with varied responses to gamified challenges and a tendency for some users to forget the app due to limited variety.

Conclusions:

• The HAPPYthalamus mobile app demonstrates usability for children with hypothalamic dysfunction but requires further refinement.
• Enhancements incorporating age-specific adaptations, behavioral change theories, and improved gamification strategies are recommended to boost engagement and support long-term healthy lifestyle adoption.