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Updated: Jun 12, 2025

Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity
Published on: January 6, 2015
Diffusing capacity and alveolar attachments to small airways in smokers with and without COPD
Yusuke Shiraishi1, Naoya Tanabe1, Atsuyasu Sato1
1Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
The number of small airway attachments in smokers relates to lung function (diffusing capacity for carbon monoxide, or DLCO). Early smoking damage impairs DLCO, even without COPD.
Area of Science:
- Pulmonary Medicine
- Respiratory Physiology
Background:
- Smoking is a major cause of lung disease.
- Chronic Obstructive Pulmonary Disease (COPD) is a significant smoking-related illness.
- Early detection of lung damage is crucial for intervention.
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