Related Experiment Video
Updated: Jun 19, 2026

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
Published on: June 11, 2011
Culture-negative liver abscess identified with plasma microbial cell-free DNA sequencing: A case report
Yuanchao Xue1, Filipe M Cerqueira1, Heather L Stevenson1
1Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.
None:
Pyogenic liver abscess (PLA) is a potentially life-threatening disease. Early diagnosis and appropriate treatment are crucial to ensure high-quality healthcare for patients with PLA. However, this is complicated by their non-specific clinical symptoms. In addition, the etiologic organisms responsible for PLA are frequently culture-negative, thus complicating clinical decision-making. Here, we report a case of PLA caused by Streptococcus intermedius, as identified via DNA metagenomic sequencing of plasma.

