Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential laboratory monitoring in autoimmune disease: a matched case-control study from Qatar primary care.

Journal of translational medicine·2026
Same author

Directional Symptom Dependencies in Multiple Sclerosis and Parkinson's Disease: A Comparative Bayesian Network Analysis.

Journal of multidisciplinary healthcare·2026
Same author

Hematological abnormalities in clinically diagnosed non-alcoholic steatohepatitis: prevalence, clinical correlates, and fibrosis risk in a case-control study from Qatar.

Frontiers in medicine·2026
Same author

Probabilistic pathways from chronic pain to suicidal ideation in Qatar: a Bayesian-Network study.

Journal of translational medicine·2026
Same author

NOTCH1 mutation status as a prognostic biomarker in T-cell acute lymphoblastic leukemia: a systematic review and meta-analysis.

BMC cancer·2025
Same author

Immune checkpoint inhibitors in pancreatic adenocarcinoma: a systematic review and meta analysis of clinical outcomes.

Frontiers in oncology·2025

Related Experiment Video

Updated: May 10, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

12.6K

Modeling chronic pain interconnections using Bayesian networks: insights from the Qatar Biobank study.

Aisha Ahmad M A Al-Khinji1,2, Dhafer Malouche2,3

  • 1College of Medicine, Qatar University, Doha, Qatar.

Frontiers in Pain Research (Lausanne, Switzerland)
|June 11, 2025
PubMed
Summary

This study reveals how chronic pain locations interconnect and vary by age and gender. Understanding these links can help create personalized pain management strategies.

Keywords:
Bayesian networkQatar Biobank (QBB)conditional probabilitiespain interdependenciesprobabilistic modelingsystemic pain

More Related Videos

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
09:00

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Published on: July 7, 2023

3.4K
Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

733

Related Experiment Videos

Last Updated: May 10, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

12.6K
Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
09:00

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Published on: July 7, 2023

3.4K
Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

733

Area of Science:

  • Epidemiology
  • Biostatistics
  • Public Health

Background:

  • Chronic pain is a complex condition with multifactorial origins.
  • Understanding the interdependencies between different pain locations and demographic factors is crucial for developing effective clinical strategies.
  • Previous research has often examined pain locations in isolation, limiting a holistic understanding of chronic pain networks.

Purpose of the Study:

  • To investigate the interdependencies among various chronic pain locations.
  • To explore the relationships between chronic pain patterns, age, and gender.
  • To provide a framework for personalized chronic pain management.

Main Methods:

  • A Bayesian network approach was utilized.
  • Data from 2,400 adult participants (18+ years) from the Qatar Biobank (QBB) were analyzed.
  • Participants were stratified into young (18-35), middle-aged (36-60), and senior (61+) age groups, with equal gender distribution.

Main Results:

  • The study identified significant direct and indirect associations between pain locations and demographic factors.
  • Younger females exhibited a higher prevalence of headaches/migraines compared to younger males.
  • Strong correlations were observed between hand and hip pain, as well as hand and neck/shoulder pain. Back pain emerged as a key predictor of generalized pain, especially when co-occurring with hand pain.
  • Knee pain prevalence was significantly influenced by age, back pain, and foot pain, particularly in older individuals.

Conclusions:

  • Bayesian network parameters reveal probabilistic interdependencies among pain locations, suggesting targeted interventions can mitigate broader chronic pain networks.
  • Demographic predispositions significantly influence downstream pain patterns, highlighting the need for personalized chronic pain management.
  • The findings offer an actionable framework for clinicians to develop individualized treatment strategies for chronic pain.