Reversible dilated cardiomyopathy caused by primary hyperparathyroidism: A case report

Area of Science:

• Cardiology
• Endocrinology
• Medical Case Reports

Background:

• Dilated cardiomyopathy (DCM) is a leading cause of heart failure, often non-ischemic.
• Primary hyperparathyroidism (PHPT) involves excess parathyroid hormone (PTH) and hypercalcemia, frequently asymptomatic.
• PHPT is a potential, often overlooked, cause of cardiac dysfunction.

Observation:

• A 52-year-old male presented with DCM, refractory hypercalcemia, dyspnea, anorexia, and abdominal distention.
• Elevated serum PTH and a parathyroid adenoma identified via sestamibi scan were noted.
• The patient underwent parathyroidectomy, confirming a parathyroid adenoma.

Findings:

• Post-parathyroidectomy, the patient's hypercalcemia resolved.
• Cardiac chamber dimensions decreased significantly after surgery.
• Marked improvement in overall cardiac function was observed.

Implications:

• This case highlights the critical link between PHPT and DCM.
• PTH level assessment is crucial for DCM patients with hypercalcemia.
• Surgical management of PHPT can reverse cardiac manifestations in DCM.