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Chronic lymphocytic leukaemia extravaganza: Vacuolated lymphoma cells

Radu Chiriac1, Lucile Baseggio1

  • 1Hematology Laboratory, Hospices Civils de Lyon, Lyon, France.

British Journal of Haematology
|June 11, 2025
PubMed
Abstract

No abstract available in PubMed .

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Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
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The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
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