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The Reverse Peroneus Brevis Flap for Preventing Major Level Amputation in Multimorbid Patients
Christopher Bibbo, Jeremy Dubin1, Deepak V Patel
1Rubin Institute for Advanced Orthopedics, LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, MD.
Annals of Plastic Surgery
|June 11, 2025
Summary
The distally based reverse peroneus brevis muscle flap offers a viable first-line option for foot and ankle soft tissue coverage in high-risk patients. This muscle flap achieved an 83% limb salvage rate, demonstrating its effectiveness in preventing major amputations.
Area of Science:
- Orthopedic Surgery
- Plastic Surgery
- Reconstructive Surgery
Background:
- Free tissue transfers often overshadow simpler local rotation flaps for foot and ankle soft tissue coverage.
- The distally based reverse peroneus brevis muscle flap presents a less complex alternative for reconstruction.
- High-risk, medically complex patients often face major amputation for lower extremity defects.
Purpose of the Study:
- To evaluate the efficacy of the distally based reverse peroneus brevis muscle flap as a primary surgical option.
- To assess flap survival and limb salvage rates in medically high-risk patients undergoing foot and ankle reconstruction.
- To identify risk factors associated with flap complications in this patient cohort.
Main Methods:
- A single surgeon's experience with the distally based reverse peroneus brevis muscle flap was retrospectively reviewed.
- Doppler examination was used for pre-operative and intra-operative flap assessment; angiography was not performed.
- Data collected included patient demographics, medical comorbidities, injury details, flap characteristics, and outcomes.
Main Results:
- Complete flap survival was achieved in 75% of patients, with 14% experiencing partial flap necrosis.
- Smoking and uncontrolled diabetes (hemoglobin A1c ≥6.5) were significantly associated with flap complications.
- An overall limb salvage rate of 83% was achieved at a mean follow-up of 6.9 years.
Conclusions:
- The distally based reverse peroneus brevis muscle flap is a suitable first-line treatment for foot and ankle soft tissue defects in high-risk patients.
- This flap offers a valuable alternative to major amputation for complex lower extremity injuries in medically compromised individuals.
- Careful patient selection and management of comorbidities like smoking and diabetes are crucial for optimizing outcomes.

