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Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
07:20

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR

Published on: February 4, 2018

[Borreliosis--still a diagnostic labyrinth]

W C Marsch, R Muckelmann

    Zeitschrift Fur Hautkrankheiten
    |August 1, 1985
    PubMed

    Insights

    Acrodermatitis chronica atrophicans and meningo-polyneuritis are infectious diseases caused by spirochetes transmitted by ticks. These conditions, following erythema migrans, can be misdiagnosed.

    Area of Science:

    • Infectious Diseases
    • Neurology
    • Dermatology

    Background:

    • Acrodermatitis chronica atrophicans (ACA) and Garin-Bujadoux-Bannwarth syndrome (GBBS) are late manifestations of Lyme borreliosis.
    • These conditions can present diagnostic challenges, potentially leading to misinterpretation.

    Observation:

    • Three case reports detail patients presenting with ACA and GBBS.
    • Initial symptoms included erythema migrans, a characteristic rash of Lyme disease.

    Findings:

    • The cases illustrate the spirochetal etiology of both ACA and GBBS.
    • The causative agent, a spirochete, is typically transmitted by the Ixodes ricinus tick.

    Implications:

    • Recognizing the spirochetal nature of ACA and GBBS is crucial for accurate diagnosis.
    • Early and correct diagnosis facilitates timely and appropriate treatment of these tick-borne illnesses.

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