Related Experiment Video
Updated: Jun 13, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Perioperative management of Endocrine disorders- practical considerations
1Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Abstract:
It is important to correctly identify and treat endocrine conditions well before, during and proceeding surgery, even if this entails delaying surgical intervention. Failure to do this has been shown to increase mortality and morbidity. Hormones are involved in controlling metabolism, cellular processes, blood pressure, blood glucose levels, calcium homeostasis as well as fluid and electrolyte balance. Disordered hormonal production can be deleterious right from the time of anaesthesia induction. Specific endocrine disorders, such as thyroid disorders, pheochromocytoma, Cushings, adrenal insufficiency, acromegaly, hypercalcemia, carcinoids and diabetes insipidus have been discussed in literature, with practical considerations. This includes alternative modality of drug administration, management of associated comorbidities, as well as optimisation of nutrient levels pivotal to the success of bariatric surgery. For the current narrative review, a search on Google, PubMed, Up-to-Date and relevant clinical practice guidelines was carried out to extract the requisite information. Optimisation of the endocrinopathy and its sequelae, geared towards achieving metabolic control starting well before the procedure, is likely to lead to good surgical outcomes.
Related Concept Videos
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
The Endocrine System
Hypoglycemia and Glucagon
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
An Overview of the Endocrine System
The endocrine system collaborates...

