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Updated: Jun 13, 2025

Separation of Aldehydes and Reactive Ketones from Mixtures Using a Bisulfite Extraction Protocol
Published on: April 2, 2018
Harnessing Electrochemistry for Direct Deoxygenative Silylation of Alcohols and Ketones
Yi-Xian Zheng1, Yuan-Xin Wu1, Li-Jian Su1
1State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China.
Abstract:
Alcohols and ketones are abundant and structurally diverse feedstocks, yet their direct transformation into organosilicon compounds remains challenging due to the difficulty in selective cleaving C─OH and C═O bonds. Here, we report an electrochemically driven deoxygenative C─Si bond formation strategy that converts alcohols and ketones directly to organosilicon compounds. The reactions operate under mild conditions without external redox reagents and sacrificial electrodes. A wide range of alcohols, including primary, secondary, and tertiary alcohols, as well as ketones, are efficiently converted to the corresponding organosilane products. Overall, this study provides a step-economical, highly efficient, and synthetically versatile platform for the direct conversion of feedstock chemicals into valuable organosilicon compounds.
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