[Recent Advances in Peripheral Immunoscore in Lung Cancer]
Fan Xu1,2, Bin Luo1, Jianhui Tian1,2
1Department of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China.
Zhongguo Fei AI Za Zhi = Chinese Journal of Lung Cancer
|June 12, 2025
Summary
Peripheral immunoscore shows promise for lung cancer prediction. This immune-based scoring system can enhance early diagnosis, treatment efficacy, and prognosis evaluation, offering a new avenue for clinical models.
Area of Science:
- Oncology
- Immunology
- Biomarkers
Background:
- Lung cancer remains a leading cause of cancer morbidity and mortality worldwide.
- Current tumor-node-metastasis (TNM) staging has limitations in accurately predicting lung cancer outcomes.
- There is an urgent need for novel clinical predictive models to guide lung cancer prevention and treatment.
Purpose of the Study:
- To systematically review the latest research on peripheral immunoscore in lung cancer.
- To explore the potential clinical applications of peripheral immunoscore in lung cancer management.
- To provide insights for developing new predictive models for lung cancer.
Main Methods:
- Review of recent scientific literature on peripheral immunoscore and lung cancer.
- Analysis of studies evaluating peripheral immunoscore for early diagnosis, treatment efficacy, adverse reaction prediction, and prognosis.
- Synthesis of findings to highlight the clinical utility of peripheral immunoscore.
Main Results:
- Peripheral immunoscore, based on peripheral immune parameters, is emerging as a valuable tool.
- It dynamically reflects the body's immune function and tumor microenvironment.
- Research indicates its potential in early diagnosis, predicting drug efficacy, and evaluating prognosis.
Conclusions:
- Peripheral immunoscore offers a comprehensive evaluation system for lung cancer.
- Its application in early diagnosis, treatment response prediction, and prognosis evaluation shows significant potential.
- Further development of peripheral immunoscore-based models could revolutionize lung cancer clinical practice.


