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Updated: Jun 16, 2025

Sequencing of mRNA from Whole Blood using Nanopore Sequencing
Published on: June 3, 2019
Global Whole-Genome Resequencing of Beef Cattle Reveals Characteristic Traits Related Genes in Pinan Cattle
Dongdong Bo1,2, Yuanyuan Wang1,2, Yilin Bai1,2
1School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China.
Abstract:
Beef cattle breed improvement holds strategic significance in the livestock industry. Pinan cattle, developed through years of selective breeding in Xinye County, Henan Province, exhibit superior traits including thin skin, fine bone structure, rapid growth, high dressing percentage, excellent meat yield, and superior feed efficiency. However, research on the genetic characteristics of Pinan cattle remains in its infancy. In this study, we investigated population genetic diversity and positive selection signals in Pinang cattle based on whole-genome resequencing data. Using a selective sweep approach, we identified 98 candidate genes associated with growth, reproduction, and immunity, along with 13 high-confidence missense mutations, which may underlie key traits in this population. Based on the critical roles of the NDN and PARVA genes in reproduction and muscle development, the predominant T allele at the NDN c.581T > A and PARVA c.893T > A loci in the Pinan cattle population may partially explain their advantages in sexual precocity and rapid growth compared to other breeds or populations. This study provides an important theoretical basis for the genetic improvement of native beef cattle and lays a scientific foundation for further investigation into the growth and development mechanisms of Pinan cattle.
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