Related Experiment Video
Updated: Jun 15, 2025

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Postoperative Pain Management: Evaluating the Role of Multimodal Analgesia
Archana Gautam1, Chetan Pande1, Meghana Pande2
1Department of Anesthesiology, Symbiosis Medical College for Women and Symbiosis University Hospital and Research Centre, Symbiosis International (Deemed University), Lavale, Pune, Maharashtra, India.
Background:
Effective postoperative pain management is essential for enhancing recovery and improving patient outcomes. Multimodal analgesia (MMA) combines different analgesic approaches to optimize pain control while reducing opioid dependence. This study evaluates the effectiveness of MMA in managing postoperative pain across various surgical procedures.
Objectives:
To assess the impact of multimodal analgesia on postoperative pain relief, opioid consumption, and associated side effects.
Methods:
A quasi-experimental study was conducted with 60 patients divided into a study group (n=30) receiving MMA and a control group (n=30) receiving standard pain management. Pain levels were assessed using the Visual Analog Scale (VAS) at 6, 12, and 24 hours post-surgery. Opioid consumption and the incidence of side effects were also recorded.
Results:
The study group reported significantly lower VAS pain scores at all time points compared to the control group. Additionally, opioid consumption was reduced, with fewer opioid-related side effects observed in the MMA group.
Conclusion:
Multimodal analgesia effectively reduces postoperative pain, minimizes opioid use, and decreases associated side effects, supporting its broader implementation in clinical pain management strategies.
Related Concept Videos
Analgesia and Pain Management
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Opioid Analgesics: Morphine and Other Natural Cogeners
Parenteral Anesthetics: Overview
Nociception
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

