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Intravenous regional anaesthesia with ketamine
Anaesthesia
|September 1, 1985
Summary
Intravenous regional anesthesia using ketamine provided good pain relief for upper limb surgery in most patients. However, patients experienced unexpected unconsciousness after tourniquet removal, which naloxone did not prevent.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Intravenous regional anesthesia (IVRA) is a common technique for limb surgeries.
- Exploring novel anesthetic agents for IVRA is crucial for improving patient outcomes.
Purpose of the Study:
- To evaluate the efficacy and safety of ketamine in IVRA for upper limb surgery.
- To assess the analgesic properties and potential side effects of ketamine when administered via IVRA.
Main Methods:
- Ketamine (40 ml of 0.5% solution) was administered via IVRA.
- The study included 14 patients undergoing upper limb surgery.
- Analgesia and patient consciousness levels were monitored.
Main Results:
- Satisfactory analgesia was achieved in 12 out of 14 patients (85.7%).
- All patients experienced transient unconsciousness upon tourniquet release.
- Naloxone administration did not prevent the observed unconsciousness.
Conclusions:
- Ketamine is effective for analgesia in IVRA for upper limb procedures.
- The occurrence of unconsciousness is a significant limitation of this technique.
- Further research is needed to mitigate the side effect of transient unconsciousness.