Related Experiment Video
Updated: Jun 15, 2025

Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
Bioactive Compounds and Biological Activities of Sarcomphalus joazeiro (Mart.) Hauenschild
Natália Kelly Gomes de Carvalho1, Mariana Pereira da Silva2, Débora Odília Duarte Leite2
1Northeast Biotechnology Network, RENORBIO, State University of Ceará, Fortaleza, Ceará, Brazil.
Abstract:
Sarcomphalus joazeiro (Mart.) Hauenschild (Rhamnaceae), commonly referred to as "juá" or "joazeiro," is a native and endemic species of the Brazilian semiarid region. This review aims to compile all information on the ethnobotanical, chemical, biological, and biotechnological aspects of the species, including data on patents. The methodology employed involved an integrative review of all published literature from 1984 to 2024. As a result, 25 articles and 18 patents were selected for this study. The species demonstrated antioxidant, antimicrobial, anxiolytic, and gastroprotective activities, among others. These bioactivities are attributed to the presence of saponins and flavonoids, main constituents of its bark and leaves, respectively. Pharmacokinetic studies suggest that nanoformulation systems can increase the solubility and absorption of these bioactive compounds. Notably, patented products derived from S. joazeiro are targeted at the food, cosmetic, and personal hygiene industries. Future research on this species is necessary to evaluate the toxicological profile, isolation of compounds, mechanisms of action, and bioavailability.
More Related Videos
07:55Author Spotlight: A Tailor-Made Sample Preparation Approach for Enhanced MALDI-IMS Analysis of Hard Palm Seeds
Published on: June 30, 2023
12:12Identification of Hemolytic and Phospholipase Activity in Crude Extracts from Sea Anemones by Straightforward Bioassays
Published on: March 29, 2022
Related Concept Videos
Structure-Activity Relationships and Drug Design
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
Adrenergic Agonists: Chemistry and Structure-Activity Relationship
Aromatic ring substitutions: Substituting the aromatic ring with –OH groups at positions 3 and 4 yields catecholamines (e.g., epinephrine), which have a high affinity for adrenoceptors. Hydrogen bonding between –OH groups and receptors enhances adrenergic activity.
Separation of...
Positive Regulator Molecules
Symbiosis
Compounds Essential to Human Function
Inorganic Compounds Essential to Human Functioning
Inorganic compounds essential to human functioning include water, salts, acids, and bases. These compounds are inorganic, i.e., they do not have a carbon-hydrogen bond. Water...
Paracrine Signaling