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Cisplatin and temozolomide combinatorial treatment triggers hypermutability and immune surveillance in experimental

Pietro Paolo Vitiello1, Benoit Rousseau2, Rosaria Chilà3

  • 1Department of Oncology, Molecular Biotechnology Center, University of Torino, 10126 Turin, Italy; IFOM ETS - The AIRC Institute of Molecular Oncology, 20139 Milan, Italy.

Cancer Cell
|June 13, 2025
PubMed

Keywords:
chemotherapycisplatincolorectal cancercytotoxic chemotherapyimmune checkpoint blockadeimmune rewiringimmune surveillancemismatch repair modulationneoantigenstemozolomide

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