Related Experiment Video
Updated: Jun 16, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Collaborative innovation during the drug discovery and development process
Xue Wu1, Mirjam Knockaert2, Paolo Blasi3
1Department of Economics and Business Administration, Ghent University, Tweekerkenstraat 2, 9000 Gent, Belgium; Department of Pharmacy and Biotechnology, University of Bologna, Via San Donato 19/2, 40127 Bologna, Italy.
Multidisciplinary collaborations are key to drug discovery innovation. This review analyzes how initiating and implementing these partnerships effectively drives positive outcomes in pharmaceutical research.
Area of Science:
- Pharmaceutical Science
- Innovation Management
- Collaboration Studies
Background:
- Drug discovery and development is complex and resource-intensive.
- Breakthrough innovations frequently arise from multidisciplinary collaborations.
- Understanding collaborative innovation is crucial for advancing pharmaceutical research.
Purpose of the Study:
- To systematically review collaborative innovation in drug discovery and development.
- To analyze current practices and identify future research directions.
- To focus on successful initiation, implementation, and outcome generation of collaborative innovation.
Main Methods:
- Systematic literature review using an evidence-based approach.
- Searched Web of Science 'All Databases' for relevant papers.
- Selected 74 articles from an initial retrieval of 737 papers for analysis.
Main Results:
- Articles were categorized by collaborative innovation phases: initiation, implementation, and closure.
- Collaborations were classified into homogeneous and heterogeneous types.
- Existing knowledge on initiating and implementing collaborative innovation was systematically reviewed.
Conclusions:
- Collaborative innovation is vital for overcoming drug discovery complexities.
- Effective initiation and implementation strategies are essential for successful partnerships.
- Further research can optimize collaborative innovation for enhanced drug research outcomes.
Related Concept Videos
Drug Discovery: Overview
Preclinical Development: Overview
Structure-Activity Relationships and Drug Design
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
Clinical Trials: Overview
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Combined Effects of Drugs: Synergism
Such synergistic combinations...

