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Published on: August 11, 2014
Application of Organoids to Investigate Virus-Host Interactions
Tong Wu1, Quan Zhou1, Chunfu Zheng2
1Kobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong Province, China.
Abstract:
Complex interactions between viruses and host cells are difficult to study via traditional models. Organoids, three-dimensional (3D) tissue-like structures derived from stem cells, have emerged as transformative tools for modeling human tissues and revealing the intricate dynamics of virus-host interactions. This chapter summarizes the relevant applications of organoids in virus-host interaction studies and provides detailed information and experimental procedures for using them to study virus-host interactions.
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