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Updated: Sep 19, 2025

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model
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Published on: February 10, 2023

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[Implementation of the guidelines for the management of toxicities from immunotherapy in first-line care]

Alice de Froidmont1, Guy Jerusalem1, Charles Pottier1

  • 1Service d'Oncologie Médicale, CHU Liège, Belgique.

Revue Medicale De Liege
|June 16, 2025
PubMed

Immune checkpoint inhibitors (ICI) have revolutionized the treatment of solid tumors. However, they can induce immune-related adverse effects (irAEs) that can affect any organ. These irAEs are different from the side effects of traditional oncological treatments and require specific management. Given the increasing use of ICI, first-line care will increasingly need to manage these irAEs. This article aims to assist in the implementation of the guidelines for managing irAEs, with a particular focus on aspects related to first-line care.

Keywords:
First-line careImmune checkpoint inhibitorImmunotherapySide effects

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