Improving Asthma Guideline Implementation in Hospital Medicine (ImAGINE): A Single-site Improvement Initiative

Daniel Herchline1,2, Michelle Mitchell1, Shanon Brannen1

  • 1From the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

PubMed

Insights

This study improved adherence to the Global Initiative for Asthma (GINA) guidelines for pediatric asthma exacerbations. Interventions increased guideline-concordant controller regimens from 39% to 71% in patients aged 6-18.

Area of Science:

  • Pediatric Pulmonology
  • Quality Improvement Science
  • Evidence-Based Medicine

Background:

  • The 2019 Global Initiative for Asthma (GINA) report recommended updated approaches for pediatric asthma management.
  • Asthma exacerbations in children require effective controller regimens to reduce morbidity and improve symptom control.
  • Baseline adherence to GINA guideline-concordant controller regimens for pediatric asthma exacerbations was suboptimal at 39%.

Purpose of the Study:

  • To increase the percentage of pediatric patients (6-18 years) with asthma exacerbations receiving GINA guideline-concordant controller regimens.
  • To improve asthma management by implementing changes based on the 2019 GINA report recommendations.
  • To achieve a target concordance rate of 50% within six months.

Main Methods:

  • Utilized the Model for Improvement framework with stakeholder input to identify key drivers.
  • Implemented interventions including education on GINA guidelines, audit and feedback for prescribers, standardized electronic health record documentation, and improved access to decision-support tools.
  • Employed electronic health record queries for patient identification and control charts for weekly data tracking.

Main Results:

  • The average baseline concordance rate for GINA guideline-concordant controller regimens was 39% with significant variability.
  • Following the implementation of interventions, a notable shift in the centerline of control charts was observed.
  • The final median concordance rate achieved was 71%, exceeding the initial study goal.

Conclusions:

  • A multifaceted quality improvement initiative successfully increased the rate of pediatric asthma patients discharged on GINA guideline-concordant maintenance regimens.
  • The study demonstrated the effectiveness of combining education, audit and feedback, standardized documentation, and decision support in improving asthma care.
  • The interventions led to a substantial improvement in adherence to the latest GINA guidelines for asthma management in children.
Abstract

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