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Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

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Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
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Long-term Potentiation01:25

Long-term Potentiation

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
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Plasticity00:58

Plasticity

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Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
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Related Experiment Video

Updated: Sep 19, 2025

Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning
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Brain Plasticity and the Labbé Procedure: Where do we stand?

Zhen Yu Wong1, Jeremias Schmidt2, Frank W de Jongh3

  • 1Department of General Surgery, Nottingham City Hospital, Nottingham, United Kingdom.

JPRAS Open
|June 16, 2025
PubMed
Summary
This summary is machine-generated.

The Labbé procedure for facial paralysis (FP) may not rely solely on brain plasticity. This review explores alternative mechanisms like trigeminal-facial neurotization for improved FP treatment.

Keywords:
Brain plasticity, lateralityFacial palsyFacial reanimation surgeryLabbé procedurePeripheral facial palsy

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Area of Science:

  • Neurosurgery
  • Neuroscience
  • Rehabilitation Medicine

Background:

  • Facial paralysis (FP) significantly impacts quality of life.
  • The Labbé procedure is a surgical option for facial reanimation.
  • The role of brain plasticity in Labbé procedure success is debated.

Purpose of the Study:

  • To review brain plasticity in the context of the Labbé procedure.
  • To discuss trigeminal-facial neurotization as an alternative mechanism.
  • To highlight areas for future research in facial reanimation.

Main Methods:

  • Literature review of studies on the Labbé procedure.
  • Analysis of evidence for brain plasticity in facial reanimation.
  • Exploration of alternative neurotization pathways.

Main Results:

  • Limited evidence supports brain plasticity as the primary mechanism for Labbé procedure success.
  • Trigeminal-facial neurotization presents a potential alternative explanation.
  • Current understanding of underlying mechanisms requires further investigation.

Conclusions:

  • Rethinking the mechanisms of the Labbé procedure is necessary.
  • Investigating trigeminal-facial neurotization could offer new therapeutic insights.
  • Further research is crucial for optimizing FP treatment and rehabilitation.