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Published on: October 11, 2024
Child and adolescent heart and lung post-transplant adherence
Melissa K Cousino1, Jill Plevinsky2, Kristin Niel3
1Departments of Pediatrics and Cardiac Surgery, University of Michigan, Ann Arbor, MI.
Improving adherence to post-transplant care is vital for pediatric thoracic transplant recipients. This review highlights factors affecting adherence and actionable strategies to enhance outcomes and quality of life.
Area of Science:
- Pediatric Medicine
- Transplantation Surgery
- Health Psychology
Background:
- Adherence to post-transplant regimens is crucial for graft and patient survival in thoracic transplantation.
- Sub-optimal adherence is a significant issue in pediatric thoracic transplant recipients.
- Adherence challenges contribute to increased mortality rates in adolescent and young adult transplant survivors.
Purpose of the Study:
- To provide an up-to-date overview of the pediatric thoracic transplant adherence literature.
- To identify multi-directional factors influencing self-management and treatment adherence.
- To highlight actionable clinical, research, and policy efforts to improve adherence.
Main Methods:
- Expert-derived review of existing literature on pediatric thoracic transplant adherence.
- Analysis of individual, family, community, system, and societal level factors.
- Synthesis of current evidence on interventions and strategies.
Main Results:
- Adherence is influenced by a complex interplay of multiple factors.
- Specific challenges exist for adolescent and young adult populations.
- Actionable strategies are needed across various levels to improve adherence.
Conclusions:
- Enhancing treatment adherence is critical for improving graft survival and quality of life in pediatric thoracic transplant recipients.
- Targeted interventions addressing multi-level factors are necessary.
- Further research and policy development are essential to support adherence.
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